Hidradenoma papilliferum with oxyphilic metaplasia. Also known as papillary hidradenoma benign, small, sharply circumscribed nodule covered by normal skin, often on labia majora or interlabial folds may ulcerate through skin and simulate carcinoma may derive from ectopic mammary tissue resembles intraductal papilloma. Histopathologically, hidradenocarcinoma papilliferum shows an appearance reminiscent of hidradenoma papilliferum, with papillary formations composed of a central core of fibrovascular tissue lined by a double layer of epithelial cells. In addition, a single lesion may contain a mixture of celltypes. The lesions usually present as an asymptomatic slowgrowing, red, firm, mobile, welldelimitated nodule that grows for a long time before resection. Histopathologically, hidradenocarcinoma papilliferum shows an appearance reminiscent of hidradenoma papilliferum, with papillary formations composed of a central core of fibrovascular. Syringocystadenoma papilliferum is an uncommon benign tumor of disputed histogenesis, 667 with a predilection for the scalp and forehead.
Cysts clinical images are available in hardcopy only. The patients underwent hemorrhoidectomy and excision of the lesion. Hidradenoma papilliferum hp is a rare, small, benign, cystic, papillary, slow growing tumor occurring in anogenital region of adult women. Nodular hidradenoma, also known as eccrine acrospiroma, is a benign adnexal skin tumour. Hidradenoma papilliferum of the vulva presenting as a. Tubules and broad, elongated fronds form an arborizing pattern and are lined with a doublelayered epithelium figures 2, 3. Hidradenoma papilliferum is a benign tumor that usually occurs in the female anogenital region. Histologically, hidradenoma papilliferum is a circumscribed cystic dermal lesion filled. Hidradenoma papilliferum article about hidradenoma. Soeprono teaches and practices dermatopathology at loma linda university, school of medicine, department of dermatology.
Syringocystadenoma papilliferum an overview sciencedirect. Papillary hidradenoma hidradenoma papilliferum benign tumor of sweat gland origin dome shaped tumor, hidradenoma benign, small, sharply circumscribed nodule covered by normal skin, often on labia majora or interlabial folds may ulcerate through skin and simulate carcinoma may derive from ectopic mammary tissue resembles intraductal papilloma. Hidradenoma papilliferum, he 10x 1990 hidradenoma papilliferum, he 40x 1994 another case, he and antibody against smooth muscle actin. Hidradenoma papilliferum is a rare tumor that occurs almost exclusively in females on the anogenital area. All hidradenoma papilliferum messages cancercompass. It is then referred to as ectopic hidradenoma papilliferum.
Hidradenoma papilliferum is an uncommon benign cutaneous adnexal tumour arising from apocrine sweat glands with predilection to the vulvar area in middleaged women 35, 36. They can be clinically confused with other lesions that can appear in this area such as malignancies and less frequently other benign neoplasms, such as lipomas, papillary hidradenoma, and epidermoid cysts 1. The histological study shows a hidradenoma papilliferum. Hidradenoma papilliferum is a benign tumour of apocrine sweat glands.
Solitary, nodule often partly solid, partly cystic. Histopathology following surgical removal indicated it represented a. The lesion is a small solitary dermal or subcutaneous nodule, most commonly on the vulva histology of hidradenoma papilliferum. It usually presents as an asymptomatic fleshcolored nodule in the anogenital area of women. Hidradenoma papilliferum is a rare benign tumor of apocrine glands. Only a single case of ductal carcinoma in situ arising in hp has been previously reported.
From the departments of pathology drs leeborg and gatter. Clear cell hidradenoma, solid and cystic hidradenoma or dermal acrospiromas. Hidradenoma papilliferum with mixed histopathologic features of. A case report from a tertiary hospital of rajasthan, india. Like other cystic skin lesions, it often clinically presents as a skincolored nodule. Hidradenoma papilliferum is a wellcircumscribed dermal nodule, usually without connection to the overlying epidermis figure 1. It has characteristic histopathological features composed of anastomosing and branching tubules, lined by columnar cells, and a basal layer of myoepithelial cells.
It is usually very small and asymptomatic, and to make a correct diagnosis is. Anastomosing and branching tubules, lined by columnar cells, and a basal layer of myoepithelial cells are the characteristic histopathological features. Hidradenoma papilliferum with a ductal carcinoma in situ com. Cooper and mac donald, in 1944, described the first case of perianal hidradenoma papilliferum 2. Hidradenoma papilliferum is a rare benign cystic tumor that originates from apocrine glands or anogenital mammary glands. In some cases the tumor displays a histopathology similar to syringocystadenoma papilliferum since they are closely related tumors which. He had had a subcutaneous tumor on his right eyebrow for 30 years. Hidradenoma papilliferum is a relatively common benign sweat gland neoplasm that arises almost exclusively in the anogenital region of women. Soepronos textbook is available on and includes detailed information on over 600 entities and includes four dvd diskettes with highresolution images that provide a virtual dermatopathology reference and guide. This was a small cyst on my vulvar i had it for about 1 year before my gyno decided it was not going away on its own and should be removed.
Hidradenoma papilliferum is a benign cutaneous adnexal neoplasm, commonly occurring in the vulva and perianal region of adult women. He told me not to worry that he was sure it was nothing. Syringocystadenoma papilliferum is an adnexal tumour which commonly occurs on the scalp, forehead or face. Hidradenoma papilliferum is a slowgrowing benign skinadnexal tumor. Hidradenoma papilliferum of the vulva pubmed central pmc. They can be clinically confused with other lesions that can appear in this area such as malignancies and less frequently other benign neoplasms, such as lipomas, papillary hidradenoma, and. The case was evaluated for malignancy, with the initial histopathology showing extensive squamous metaplasia but ultimately found to have hp. The lesion contained cells with papillary folds, tubules, cystically dilated spaces, and lumen lined by columnar cells with decapitation secretion, compatible with hidradenoma papilliferum hp figures 2 and 3. Each presented clinically with a small, solitary tumor in the anogenital region.
Interlaboratory comparison of estrogen receptor analysis in parayn sections by a monoclonal antibody to estrophilin h222. The american journal of dermatopathology, 34 1, 104109. Two female patients aged 39 and 35 presented with perianal masses with hemorrhoids. Lower power view of another case of hidradenoma papilliferum showing papillary and cystic areas in a collagenous stroma. What is the prognosis of hidradenoma papilliferum of vulva. I have just been diagnosed with hidradenoma papilliferum. Papillary hidradenoma article about papillary hidradenoma. Hidradenoma papilliferum histopathology this feature is not available right now. Although this lesion is frequently encountered in the pediatric population, sp can occur at any age. Hidradenoma papilliferum is an uncommon benign tumor that is located almost exclusively in the vulvar and anal areas. We describe a case of an 26yearold man that presented. A cytomorphological evaluation on fine needle aspiration cytology jitendra g nasit 1, gauravi dhruva 2 1 department of pathology, government medical college and sir sayajirao general hospital, baroda, gujarat, india 2 department of pathology, pandit deendayal upadhyay government medical college and hospital, rajkot, gujarat, india.
Pathology of syringocystadenoma papilliferum dr sampurna. Department of pathology, maharashtra institute of medical education and research. Most often, it presents as a raised warty plaque and is associated with alopecia when on the scalp. It is benign tissue not cancerous but is often confused clinically with carcinoma of the vulva because of its tendency to ulcerate. Hidradenoma papilliferum of the vulva with extensive squamous. Hidradenoma definition of hidradenoma by medical dictionary. Hidradenoma papilliferum, also called papillary hidradenoma, is benign tumour arising from apocrine glands see sweat gland lesions. Pathology of syringocystadenoma papilliferum dr sampurna roy md. Hidradenoma papilliferum is a benign cystic tumor originated in apocrine sweat glands of. The endocrine glands, or ductless glands, discharge their secretions hormones directly into the blood.
Papillary hidradenoma, vulva, he 40x 5982 hidradenoma papilliferum, sma 40x 5986. Hidradenoma papilliferum with a ductal carcinoma in situ. All patients were women ranging in age from 29 to 74 years. Syringocystadenoma papilliferum sp is a benign neoplasm which commonly occurs on the scalp and head. Outcomesresolutions the prognosis for hidradenoma papilliferum of vulva is excellent with appropriate treatment, since it is a. Dec 31, 2019 hidradenoma papilliferum is a rare benign cystic tumor that originates from apocrine glands or anogenital mammary glands. Pdf on jun 1, 2018, rogerio nabor kondo and others published ectopic hidradenoma papilliferum find, read and cite all the research you. Two female patients aged 39 and 35 presented with perianal masses. Microscopically, in addition to classic histopathological features. Cylindroma dermal cylindroma syringocystadenoma papilliferum papillary hidradenoma hidrocystoma apocrine gland carcinoma apocrine nevus.
Most cases of hidradenocarcinoma papilliferum originate from a preexisting hidradenoma papilliferum, and the anogenital region is the most common location. Hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammarylike glands. A 32yearold female patient presented with an asymptomatic nodule of 4 months duration in the vulva. It has characteristic histopathological features composed of. Nirmala d, rajnish k, sunita s, nidhi r 2011 hidradenoma papilliferum of the vulva. Glands are divided into two main groups, endocrine and exocrine. A papillary hidradenoma, also hidradenoma papilliferum, is a sharply circumscribed nodule or benign tumor of the apocrine gland usually found on the labia majora or the interlabial folds. Papillary cystadenoma of the lower lipmimicking hidradenoma. Hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammary like glands. Read papillary cystadenoma of the lower lipmimicking hidradenoma papilliferum, journal of cutaneous pathology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Hidradenoma papilliferum of the vulva with extensive. Histopathology revealed a dermal tumor with no connection to the overlying epidermis. A case of hidradenoma papilliferum with mixed features of syringocystadenoma papilliferum scap and anogenital mammary. Currently, there are no known methods to prevent hidradenoma papilliferum of vulva occurrence. The clinical characteristics of this tumor may be confusing, since it is uncommon. Rarely these tumours are found on the trunk, the lower extremities, ear canal and eyelid. Hidradenoma papilliferum is a benign cystic tumor, predominant in women aged 3050 years. This large tendon based mass was clinically suspected to represent a giant cell tumor of the tendon sheath. Skin nonmelanocytic tumor hidradenoma papilliferum. Hidradenoma papilliferum hp is a benign, cystic, papillary apocrine gland tumor that occurs almost exclusively in women in anogenital region 1. Media in category histopathology of papillary hidradenoma the following 10 files are in this category, out of 10 total. Syringocystadenoma papilliferum on the chest is rare. Sep 28, 2018 hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammarylike glands. Hidradenoma papilliferum hp is a benign cutaneous adnexal neoplasm occurring mainly in the anogenital region of adult women and has features analogous to intraductal papilloma of the breast.
It is benign tissue not cancerous but is often confused clinically with carcinoma of the vulva because of. Papillary hidradenoma, also hidradenoma papilliferum. A rare case of hidradenoma papilliferum journal of. Hidradenoma papilliferum is a rare benign cystic and papillary neoplasm.
Syringocystadenoma papilliferum of the external ear. Papillary hidradenoma is also known as hidradenoma papilliferum, is an uncommon lesion which. Hidradenoma papilliferum with oncocytic metaplasia. Here, we describe 2 cases of hidradenoma papilliferum of the anus. Cytology, histopathology, hidradenocarcinoma, inguinal mass, metastasis. Jul 31, 20 dermatopathology reference describes syringocystadenoma papilliferum histopathology including histologic features and provides links to additional medical references. How can hidradenoma papilliferum of vulva be prevented. Rare cases of ectopic nongenital hidradenoma papilliferum have been described. Hidradenoma papilliferum hp is an uncommon benign cutaneous adnexal neoplasm of the anogenital region commonly seen in middleaged, caucasian females. Diagnostic pitfalls in syringocystadenocarcinoma papilliferum. Sialadenoma papilliferum is a rare salivary gland tumor clinically resembling papilloma originating probably from the excretory duct. Mri characteristics of the lesion were atypical for this diagnosis.
This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment. Pdf on nov 10, 2017, kafil akhtar and others published papillary hidradenoma of vulva. Reported here are 18 cases of hidradenoma papilliferum with oxyphilic metaplasia. It is characterized by a biphasic growth pattern of exophytic squamous component and endophytic glandular component.
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